Within the EC funded LIFE project VERMEER, a new software system was develop with the aim to identify risky substances and suggest safer alternatives as remedy. This strategy was drawn up supporting the idea that for the environmental sustainability and the health of workers and consumers, the substitution of hazardous chemicals and the implementation of greener technologies are increasingly important.

The software, freely available, has been designed taking into account the level of safety, the functional uses and a similarity algorithm as cornerstones of the architecture.

To determine the level of safety, a series of authoritative lists have been taken into account and the safety class emerging from the systematic evaluation and integration of each list was adopted. Then, a hierarchical ontology of functions to enforce and facilitate the substitution process was developed. Each ingredient is associated to a specific functional use. Finally, a read-across analysis enforces the substitution process making the substitution possible even when the ingredient is not included in the archive.

An approach that incorporates together the level of safety, functions and similarity in a high-throughput way, would allow to easily recognize potential functional substitutes meeting the safety and the similarity criteria for a further and deeper evaluation.

Software Features

Download Instructions

ToxEraser Cosmetics is a JAVA application that works on every operating system (Windows/Linux/Mac) supporting Java.

Before proceeding, please check what version of Java is installed in your OS and if the JAVA_PATH environment variable is correctly set (for further details, please refer to Oracle documentation).

ToxEraser Cosmetics works with Java 8 or OpenJDK Java 11+: depending on what version is installed or set in your operative system please follow the instructions below:

JAVA 8: Download and unpack the zipped file. To start the application, move to the application folder and run the file starter.bat (on Windows platforms) or starter.sh (on Linux platforms).

OPEN JDK JAVA 11 or greater: Download and unpack the zipped file. To start the application you can just run the file ToxEraserGUI-0.8.6.jar. On most systems, it is enough to double-click it. If you are not able to directly run it, open a command line window (like Command Prompt on Windows systems or BASH shell on Linux), move to the application folder and type:

java -jar ToxEraserGUI-0.8.6.jar


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